William Andrew Wynne (March 27, 1869 – August 7, 1951) was a professional baseball pitcher.

Wynne went to school at Wake Forest University and began his professional career with the Columbia Senators in the South Atlantic League in 1892.

On August 31, 1894, Wynne started the second game of a doubleheader against the Philadelphia Phillies.

He pitched a complete game, allowing eight earned runs.

This biographical article relating to an American baseball pitcher born in the 1870s is a stub.