BioSystems is a monthly peer-reviewed scientific journal covering experimental, computational, and theoretical research that links biology, evolution, and the information processing sciences.

[2]In 1972 the journal was renamed Currents in Modern Biology: Bio Systems, which was shortened to BioSystems in 1974.

Previous editors include J.P. Schadé, Alan W. Schwartz, Sidney W. Fox, Michael Conrad,[3] Lynn Margulis,[4] David B. Fogel, Gary B. Fogel, George Kampis, Francisco Lara-Ochoa, Koichiro Matsuno, Ray Paton, and W. Mike L. Holcombe.

The special issue "Symbiogenesis and Progressive Evolution" (2021) is dedicated to Boris Kozo-Polyansky and Lynn Margulis and contains articles about these scientists, and also includes an annotated translation of the article by Konstantin Merezhkovsky, in which the concept of symbiogenesis was first outlined.

[7] The special issue "Biological Thermodynamics: Bridging the gap between physics and life" (2024) is dedicated to Ervin Bauer and contains biographical[8][9] and theoretical[10] articles about him, as well as English translations of his major works.