Biofabrication is a branch of biotechnology specialising in the research and development of biologically engineered processes for the automated production of biologically functional products through bioprinting or bioassembly and subsequent tissue maturation processes;[1] as well as techniques such as directed assembly, which employs localised external stimuli guide the fabrication process; enzymatic assembly, which utilises selective biocatalysts to build macromolecular structures; and self-assembly, in which the biological material guides its own assembly according to its internal information.
Bioprinting: This method uses computer-aided design to layer living cells and biomaterials, constructing complex three-dimensional structures that mimic natural tissues.
Bioprinting allows for precise placement of multiple cell types, enabling the creation of heterogeneous tissue structures.
[3] Biofabrication allows researchers to combine fabrication techniques with 2d/3d printing and biomanufacturing and bioassembly of living 3d functional biological products using smart and cytocompatible biomaterials[3] Scientists are developing techniques to bio fabricate tissues and organs to combat the global shortage of organ donors.By creating scaffolds that support cell growth and differentiation simple tissues like skin and cartilage have been developed and are already used in clinical settings.
This promotes faster healing and fewer post-transplant complications as they are custom made from the patients cells so this eliminate graft rejection.