Topics covered include development, neurobiology, and immunology, as well as theoretical or biophysical modelling.

The journal is currently published monthly by Wiley-Blackwell on behalf of the Société Française des Microscopies and the Société de Biologie Cellulaire de France.

[3][4] Articles were originally published in either English or French, with summaries in both languages.

[6] Biology of the Cell is indexed by BIOBASE, BIOSIS, CAB International, Cambridge Scientific Abstracts, Chemical Abstracts Service, Current Contents/Life Sciences, EMBASE/Excerpta Medica, MEDLINE/Index Medicus, and ProQuest Information and Learning Articles are primarily research and reviews.

The editor-in-chief of this journal is René-Marc Mège, a team leader at the Institut Jacques Monod.