In the same year, the building, which had been under the care of custodian Marietta Camerlengo,[5] was acquired by the Italian State, which immediately began restoration and arrangement works that were completed in 1938.

The museum, set up on the first floor of the birthplace of Gabriele D'Annunzio, consists of nine rooms and houses furnishings, period furniture, and objects belonging to the writer and his family.

The room is dedicated to D'Annunzio's childhood and contains some educational panels with photographs and quotes from his works, as well as his high school diploma from the Royal Convitto Cicognini of Prato (1881), the decree appointing Francesco Paolo Rapagnetta-D'Annunzio as Mayor for the three-year period 1879–1881, and the certificate of honorary citizenship to D'Annunzio from the Municipality of Chieti on the occasion of the first theatrical performance of "La Figlia di Iorio" (1904).

It exhibits two lithographs depicting "Vittorio Emanuele II, King of Italy" and "Giuseppe Garibaldi in Marsala", the first by Pietro Barabino and the second by Roberto Focosi; portraits of the adoptive parents of Francesco Paolo Rapagnetta-D'Annunzio ("Anna Giuseppa Lolli" and "Antonio D'Annunzio") and the painting The Rape of Proserpina, all by an anonymous artist of the 19th century.

It contains a watercolor painting by Michele Cascella, titled Luisa d'Annunzio's Room (1940), two statuettes made of tow and sculpted papier-mâché depicting St. Anne and Mary as a child, from the 19th century, and 19th-century lithographic prints (The Last Supper of St. Gregory the Great by Paolo Veronese, an Immaculate Madonna by F. De Matteis, a Presentation of Mary at the Temple by Titian, and the Holy Family with St. John the Baptist by Raphael).

It contains educational panels related to the urban development of the city, the church of S. Cetteo and the Cathedral, the reconstruction of the house's restoration works between 1926 and 1938, the marriage of Gabriele D'Annunzio with Maria Hardouin (1883), and the actress Eleonora Duse.

It also displays two honorary General of Division uniforms, two caps (one of Lieutenant Colonel and one of Major of the Lancieri di Novara), and period photographs.