[1] He was made Bishop of Oxford in 1674, and in the following year was translated to the see of London, and also appointed Dean of the Chapel Royal.

He held several conferences on the subject with the clergy of his diocese; and in the hope of influencing candid minds by means of the opinions of unbiased foreigners, he obtained letters treating of the question (since printed at the end of Edward Stillingfleet's Unreasonableness of Separation) from Le Moyne, professor of divinity at the University of Leiden, and the famous French Protestant divine, Jean Claude.

On the accession of James II in February 1685 he consequently lost his seat in the council and his position as Dean of the Chapel Royal; and for his firmness in refusing to suspend John Sharp, rector of St Giles's-in-the-Fields, whose anti-papal preaching had rendered him obnoxious to the king, he was himself suspended[4] by James's Ecclesiastical Commission in mid-1686.

He performed the ceremony of their coronation as the Archbishop of Canterbury William Sancroft considered himself still bound by his oath of allegiance to James II.

During the reign of Anne he remained a member of the privy council, and was one of the commissioners appointed to arrange the terms of the union of England and Scotland; but, to his bitter disappointment, his claims to the primacy were twice passed over.