Treaty #2 negotiations took place in Detroit and involved Pottowatomie, Wendat, Ojibwe, and Odtawa leaders.

The area was a dense Carolinian forest with wild elk, bears, wolves, and eagles.

In 1837, James W. Little, a militia officer and land speculator of neighbouring Raleigh Township, purchased land at the intersection of Ridge Road and Communication Road, the latter planned by Lieutenant-Governor John Graves Simcoe to connect the town of Chatham with Lake Erie.

Historians Dr. Fred Landon and Alvin Armstrong state that the town got its name after resident Mungo Samson recited "The Battle of Blenheim" poem at the Samuel Brundage Inn.

A fire department was established in 1891 and three years later was followed by railway that traveled through Blenheim to Windsor.

In the municipality of Chatham-Kent, Blenheim is a part of the South-Kent region which is represented by 3 councillors: Anthony Ceccacci, Mary Clare Latimer, and Trevor Thompson.

These include: The Ridge Landfill, owned by Waste Connections of Canada, is located in Blenheim.

[17] Blenheim's slogan is "Experience Unique Shopping", referring to its selection of boutiques and specialty stores.

In July, downtown businesses offer discounts during Ontario's longest running carnival-sidewalk sale, the Cherry Fest and Sidewalk Days.

Longtime organizer of the Cherry Fest, J.P. Huggins, was named Citizen of the Year by the Chatham-Kent Chamber of Commerce in 2021.