He is best known for his roles in Time of the Comet and Dossier K. Destani was born in Stolberg near Aachen, West Germany.

At 14 years of age, Destani made his acting debut in the Albanian TV film Atje ku nuk lind dielli (Where the sun doesn't rise).

He attracted significant public attention in Southeast Europe by playing the part of the main character "Beni" in the Kosovar TV production Metropolet (director: Sunaj Raca).

The successful cooperation with the well-known director Sunaj Raca was continued in 2005 in the motion picture Kosova - Desperate Search.

He was the associate producer of the Macedonian cinema production The Great Water (directed by Ivo Trajkov) shot in 2004.