Blessing in Disguise was Metal Church's final release on Elektra Records, and the first album not to feature the vocals of David Wayne, due to his departure to form the band Reverend.

This album marked the band's debut with vocalist Mike Howe (formerly of Heretic) and guitarist John Marshall, replacing Wayne and Kurdt Vanderhoof respectively.

Blessing in Disguise also marked the second and last time Metal Church had worked with Terry Date, who also produced the band's 1984 self-titled debut album.

Although Vanderhoof was technically no longer an official member of the band at this point, he composed the music and lyrics for seven of the album's nine songs and appears as a guest musician.

judged Blessing in Disguise "a hit-and-miss affair" that does not "live up to the standards set on (Metal Church) 1984 debut", lamenting "a lack of direction, an absence of focus that causes the record to fluctuate between greatness and mere mediocrity".

"[8] Martin Popoff in his Collector's Guide to Heavy Metal praised Howe's performance and Date's production, which turned "the band into an updated, renovated tower of strength, a guitar-driven machine set to stun.