[1][3] Blitzing is a higher-risk strategy, as fewer defensive players are left to cover receivers or to defend against running plays.
[4] Chuck Drulis is widely credited with inventing the safety blitz in 1960 while serving as defensive coordinator of the St. Louis Cardinals.
Any other player is available to block, or to be a target for a pass, depending on the play design and modification by the quarterback and center based on what they see the defense doing.
The defense does not and cannot cover all offensive players, but rather through the blitz, is proactively involved in pressuring the quarterback—specifically, trying to sack them, throw off their timing, or force them to make an error such as an interception or fumble.
Advantages gained by blitzing are obvious: proactively disrupt the offense's play before it develops and cause enough pressure on the quarterback to force him into a turnover, sack, or incomplete pass.
They communicate with each other at the line of scrimmage using code words that shift the protection to the blitzing player's side, thus strengthening their blocking front.
Second, the tight man bump and run technique typical of blitz scheme cornerbacks can be defeated with aggressive wide receiver release moves.
One of those techniques is called "throwing hot," which entails intentionally leaving one blitzing defensive player unblocked.
The offensive line usually makes pre-snap adjustments so that the "free" rusher is clearly within the QB's field of vision.
The QB sees the free rusher or blitzing LB/CB and knows that the receiver will sight adjust accordingly and run a route that takes him into the hole left by the defender.
This is a well timed offense where the quarterback throws the ball quickly to avoid the rush, but still allow the wide receiver to get behind the blitzing players.