A line (rope) is reeved through the sheaves, and maybe through one or more matching blocks at some far end, to make up a tackle.
In general the more sheaves in the blocks that make up a tackle, the higher its mechanical advantage.
The matter is slightly complicated by the fact that every tackle has a working end where the final run of rope leaves the last sheave.
Some blocks are used to increase mechanical advantage and others are used simply to change the direction of a line.
A single, large, sail-powered warship in the mid-19th century required more than 1,400 blocks of various kinds.