Blood Brothers 2 is an anthology of short adventures published by Chaosium in 1992 for the Lovecraftian horror role-playing game Call of Cthulhu.

Like the first book, Blood Brothers 2 is an anthology of nine short adventures that are based on themes, monsters and plots taken from classic B movies.

[1] The adventures include references to Gidget, High Plains Drifter, and Mexican lucha libre wrestlers.

[2] In the November 1992 edition of Dragon (Issue 187), Allen Varney enjoyed the generous serving of B-movie humor, saying, "Cue the theremin!

"[2] Wayne Ligon reviewed Blood Brothers 2 in White Wolf #35 (March/April, 1993), rating it a 4 out of 5 and stated that "All of the scenarios here provide lots of spirited film fun, and I heartly recommend BB2.