It is set in Toronto, Ontario, and features a 4-and-a-half century old vampire, Henry Fitzroy, assisting private investigator Vicki Nelson in dealing with crime committed via paranormal elements, a similar premise to an earlier series also set in Toronto, Forever Knight.
It premiered in the United States on March 11, 2007, on Lifetime Television, and during fall of 2007 on City and Space in Canada.
Blood Ties, set in Toronto, Ontario, centres on Vicki Nelson (Christina Cox), a former Toronto Police Service officer who left the force to become a private investigator when her eyesight begins to degenerate from retinopathia pigmentosa.
The mutual attraction between them is complicated by Vicki's relationship with former partner and lover Mike Celluci.
The "Smoke" book series is a sequel to Huff's "Blood" book, in which the characters are Tony Foster (character replaced by Coreen in Blood Ties) and Henry Fitzroy, dedicated to solving mysteries and combating supernatural threats.