[citation needed] The bridge was dedicated on November 19, 1914, with what the Pittsburgh Post described as a "monster celebration" which included a wedding for a local couple performed at the midpoint of the span.

The replacement crossing was erected in 1986, after the previous bridge was deemed deficient after years of heavy traffic, including that of popular Pittsburgh Railways streetcar lines until their 1960s conversion to buses.

On the Bloomfield side of the bridge, connections are made to Liberty Avenue, the commercial heart of the traditionally Italian (and increasingly Asian) neighborhood.

The Bloomfield Bridge spans a large number of railroad tracks, which are portions of lines managed by CSX and Norfolk Southern.

Originally known as Dean's Field, it is historically significant as the place where Johnny Unitas played semi-pro football before jumpstarting his NFL career.