Directed by Matt Stawski, the film stars Traci Paige Johnson as the voice of Blue, alongside Josh Dela Cruz, Donovan Patton, and Steve Burns.

During their search for clues, they also come across Broadway actor, Ali Stroker, who teaches them that practicing for something makes it less overwhelming.

During the ride, they spot Steve, Joe, Mr. Salt, Tickety Tock, and Slippery Soap, and they join them.

Rainbow Puppy and the director see Josh singing on the Jumbotron and return to the theater to tell him they want him to play the lead role in the show.

In a mid-credit scene, as he is getting ready for bed, Josh tells the audience that the movie is over and he and Blue sing the “So Long Song”.

[2] The film's soundtrack album was released on digital platforms by Republic Records Kids & Family label, on the same day.

[7] In a promotion for the film sponsored by Nickelodeon, minor league ice hockey team Atlanta Gladiators wore Blue's Clues jerseys for their match against the Orlando Solar Bears on November 4, 2022.

[11] Marco Vito Oddo of Collider gave the film a "B" rating, writing "As a result, Blue's Big City Adventure is a movie aimed at preschoolers that's also enjoyable for adults, with exciting musical numbers that help break the simple story and explore the street art history of New York City.

"[12] In a positive review, Calum Marsh of The New York Times praised Dela Cruz's performance, saying he brought "unbridled charisma to a role that is basically a glorified kindergarten teacher".