[1] Blue Ridge League play officially began in 1915 with six teams from Chambersburg, Frederick, Gettysburg, Hagerstown, Hanover and Martinsburg.

Due to the aftermath of the war and the 1918 flu pandemic, the Blue Ridge League did not resume operations until 1920, with Chambersburg, Frederick, Hagerstown, Hanover and Martinsburg rejoining the action, as well as the addition of the Waynesboro franchise to bring again the six-team format.

Gradually, six Major League Baseball franchises started their affiliation with the league, among others Cleveland Indians (Frederick), Detroit Tigers (Hanover), New York Yankees (Chambersburg), St. Louis Cardinals (Waynesboro) and Philadelphia Athletics (Martinsburg), Washington Senators (Hagerstown).

But after the Wall Street crash of 1929, Detroit and St. Louis dropped their affiliations due to heavy financial losses.

The Presidents in the history of the league were Joe Ryan (1946), Stanley F. Radke (1947-'48), Judge E. C. Bivins (1948-'49) and John B. Spiers (1950).