Coble led a regional effort to develop the Three Rivers Greenway, the EdVenture Children's Museum, CanalSide, and the Columbia Convention Center.
In 1994 Coble and Columbia business leaders brought a lawsuit to remove the Confederate Flag from the Dome of the South Carolina Statehouse.
The legal action was based on the fact that in 1961 the South Carolina Legislature raised the Confederate Flag over the Statehouse by a resolution rather than by statute.
Also, during Coble's time as mayor, Columbia established sister city relationships with Kaiserslautern, Germany; Cluj-Napoca, Romania; Plovdiv, Bulgaria; Chelyabinsk, Russia; and Yibin, in the Sichuan Province, China.
At his retirement Columbia City Council named the portion of the Three Rivers Greenway behind EdVenture Children's Museum, Coble Plaza in his honor.
On April 15, 2015, Coble had a heart attack in the South Carolina Statehouse while working there as a lobbyist and lawyer, but made a full recovery by August.
Beth Coble founded the "First Ladies Walk for Life" by the Palmetto Health Foundation which raised funds for breast cancer research.