In 2016, Eckstein published Footnotes from the World's Greatest Bookstores (Penguin Random House), which became a New York Times bestseller.

Eckstein's cartoons have appeared in The New Yorker, The New York Times, MAD magazine, Reader's Digest, and many other publications.

The book serves as a family-friendly bucket list, highlighting quirky facts, amusing anecdotes, and the importance of art, history, and community in museums.

Inspired by the struggles museums faced during the COVID-19 pandemic, Eckstein's work aims to raise awareness of these institutions while providing an entertaining and educational experience for readers.

He has also spoken at over 200 TV and radio shows, including Good Morning America, and at events such as the Miami Book Fair and the Norman Rockwell Museum.