In 1946, he returned to baseball and spent the entire campaign on the Dodgers' MLB roster, playing in 62 games as a utility infielder for a Brooklyn team that finished in a dead heat for the National League pennant before falling to the eventual World Series champion St. Louis Cardinals in a tie-breaker series.

He spent all of 1947 and most of 1948 in Triple-A, where he sustained two serious injuries: a fractured skull from a beanball in 1947 and a badly sprained hand in the latter year.

[2] After appearing in a total of nine games for the Dodgers in 1948 and 1949, he was traded to the Chicago Cubs for fellow infielder Hank Schenz on May 16, 1949.

As a Cub, Ramazzotti experienced his most sustained success in professional baseball, appearing in 275 games over 41⁄2 National League seasons, and batting .262, .247 and .284 in the three campaigns spanning 1950 to 1952.

He had two four-hit games, both in 1949, a year in which, ironically, he struggled badly at the plate, batting only .179 with 34 total hits in a Chicago uniform.