Bob Van Reeth started working as an architect in 1965 with designing buildings in Mechelen and Kalmthout.

In 1972, he became a teacher at the Nationaal Hoger Instituut voor Bouwkunst (The National Higher Institute for Architecture) in Antwerp.

Later buildings include in 2007 a new wing for the Westvleteren Abbey, and the black-and-white Huis Van Roosmalen facing the Scheldt in Antwerp.

[2] He also leads the company AWG (Architect Work Group) Architecten, which won the architectural concours for the design of a memorial and documentation centre about the Holocaust in Mechelen.

[3] In January 1998, Van Reeth became the first Flemish Government Architect (Vlaams Bouwmeester), a function he held until 1 June 2005 when Marcel Smets succeeded him.