[1] He was assigned immediately to the Independence Yankees of the Kansas–Oklahoma–Missouri League, where he posted a 12-11 record with a league-leading 240 strikeouts in 185 innings, helping his team to win the regular season pennant and the playoffs.

[2][3] Wiesler gained a promotion to the Joplin Miners in 1950, and he simply dominated, going 15-7 with 11 complete games and two shutouts, while leading the Western Association with a 2.35 ERA and 277 strikeouts, en route to a league pennant and an All-Star recognition.

[2][4] The strong armed lefty opened 1951 with the Kansas City Blues of the American Association, and he responded with a 10-9 mark and a 2.92 ERA in a career-high 194 innings, striking out 162 batters to claim his third strikeout title in a row.

[1] Prior to the start of the 1956 season, he was traded to the Senators along with Lou Berberet, Whitey Herzog, Herb Plews and Dick Tettelbach, in exchange for Bobby Kline and Mickey McDermott.

[2] In between, he played winter ball with the Leones del Caracas club of the Venezuelan League in the 1954–1955 tournament, as part of a pitching staff that included Don Bessent, José Bracho, Howie Fox, Bill Werle and Luis Zuloaga.