Robert Francis Keefe (June 16, 1882 – December 6, 1964) was an American pitcher in professional baseball.

He played in Major League Baseball (MLB) for the New York Highlanders and Cincinnati Reds.

Keefe started his professional baseball career with the Sacramento Senators in 1903, the first year of the Pacific Coast League (PCL).

[1] In 1911, Keefe made it back to the majors with the National League's Cincinnati Reds.

After his baseball career ended, Keefe returned to the Folsom area, where he worked for the Natomas Gold Dredging Company.