Bombesin is a 14-amino acid peptide[1] originally isolated from the skin of the European fire-bellied toad (Bombina bombina)[2] by Vittorio Erspamer et al. and named after its source.

[3] It has two known homologs in mammals called neuromedin B and gastrin-releasing peptide.

Together with cholecystokinin, it is the second major source of negative feedback signals that stop eating behaviour.

[3] Iwabuchi et al. 2003 discovered a chicken (Gallus domesticus) receptor which is homologous to both the mammalian BB3 and fBB4 and so they named it chBRS-3.5.

[3] Erspamer 1988 finds bombesin has a similar effect on the chicken to ranatensin, unreliably increasing or decreasing blood pressure.