[2] The tachykinin family is characterized by a common C-terminal sequence, Phe-X-Gly-Leu-Met-NH2, where X is either an Aromatic or an Aliphatic amino acid.

The genes that produce tachykinins encode precursor proteins called preprotachykinins, which are chopped apart into smaller peptides by posttranslational proteolytic processing.

The genes also code for multiple splice forms that are made up of different sets of peptides.

Tachykinins[3][4][5] excite neurons, evoke behavioral responses, are potent vasodilators, and contract (directly or indirectly) many smooth muscles.

All are members of the 7 transmembrane g protein-coupled family of receptors and induce the activation of phospholipase C, producing inositol triphosphate.