Despite losing in the 2016 Philippine vice presidential election and his subsequent electoral protest, Marcos expressed his interest in running again for a national position in 2022.

[11] His candidacy faced staunch opposition from various groups, particularly due to his father's regime, marked by widespread corruption and human rights abuses.

Marcos ran in the 2016 Philippine vice presidential election as the running mate of Miriam Defensor Santiago.

A highly contested race, Marcos ultimately lost to then congresswoman Leni Robredo by 263,473 votes or by 0.64 percent,[19] the narrowest margin since the 1965 vice presidential election.

[25] According to his wife, Liza, Marcos was watching Ant-Man, a movie about an ex-convict thief turned Avenger superhero, when he told her "Okay, we're gonna do this... run for the presidency".

However, despite being a frontrunner in early opinion polls, she did not file a candidacy for a national position; she instead ran for re-election in the Davao mayoral race.

Hours later, Marcos said in a statement that, "Mayor Inday Sara Duterte and I have finished the process for the partnership that our supporters have been hoping for — BBM-Sara for 2022.

"[33] Formed on November 29, 2021, the UniTeam Alliance is a loose electoral coalition supporting the candidacies of Bongbong Marcos and Sara Duterte in the 2022 presidential elections.

[43] While most tickets had their proclamation rallies in the respective hometowns of the presidential candidate, the Marcos and Duterte tandem started their campaign at the Philippine Arena in Bulacan.

[47][48] The local government later clarified that it was distributing cash aid and that it was scheduled after the rally on the same venue, while the PFP denied claims that it was engaging in vote buying.

[125] Polls conducted by Pulse Asia and OCTA Research in December 2021 showed Marcos at 53 and 54 percentage points respectively.

[126][127] According to Pulse Asia director Ana Maria Tabunda, this was the first time a presidential candidate held a majority preference in their polls.

[128] By early 2022, Marcos emerged as a clear frontrunner in all major polls, leading by at least 30 percentage points ahead of the next candidate, Leni Robredo.

The petition alleges that Marcos committed material misrepresentation in his COC when he stated that he was eligible to run for office despite his 1995 tax case and his failure to submit those documents is a crime of moral turpitude.

According to the Omnibus Election Code, a person who committed a crime involving moral turpitude is barred from holding public office.

A group composed of martial law victims represented by lawyer Howard Calleja filed a petition-in-intervention to join this petition against Marcos' candidacy on November 8.

The commission rejected the three interventions on December 13 and stated that it will not entertain similar submissions in the future after causing "unduly delay" on the main petition's status.

In a ruling signed by commissioners Antonio Kho and Rey Bulay, the petition was denied due to lack of merit, stating that Marcos did not commit material misrepresentation in his COC and that he is not perpetually disqualified from seeking office.

[145] On November 17, 2021, the Campaign Against the Return of the Marcoses and Martial Law (CARMMA) led by Bonifacio Ilagan filed the first disqualification plea against Marcos.

She also asserted that the preliminary conference was delayed to accommodate Guanzon's request to take part in the proceeding and broadcast the hearing, that there was no internal agreement on the January 17 deadline, and that she has allegedly tried to influence her decision on the case.

[156] The petitioners welcomed Guanzon's vote while Marcos' party denounced the disclosure and urged the COMELEC en banc to investigate and penalize her.

[161][162] The 44-page resolution cited the Supreme Court earlier pronouncement that failure to file tax returns is not a crime involving moral turpitude.

The resolution also affirmed that the 1977 National Internal Revenue Code did not carry the penalty of perpetual disqualification; this would only take effect under Presidential Decree 1994 on January 1, 1986.

[167] The electoral commission junked the petition on December 18, 2021, citing insufficient evidence and that Marcos has established his bonafide intention to run.

[181] On February 25, 2022, several groups protested against Marcos' candidacy and commemorated the anniversary of the People Power Revolution in EDSA.

[196][200] This proposed online platform aims to allow students and teachers to access digital learning materials and communicate securely.

Marcos vows to pursue an independent foreign policy and plans to treat other countries as "friends and hopefully allies."

[201] After the onslaught of Typhoon Rai, he stated that he aims to intensify urban planning in the country and the cleanup and development of floodways.

The UniTeam has also mentioned plans to offer zero-interest loans to make bicycles more affordable for Filipinos and roll out similar bike lane networks in other urban centers as part of their vision for a seamless intermodal transportation system in the country.

[208] In a townhall meeting on March 28, 2022, he stated that he will support laws protecting LGBT rights, and also sign a same-sex union bill if it were to be passed by Congress.