B. lesdainii B. neotropica Botryolepraria is a genus of saxicolous (rock-dwelling), byssoid (cottony) lichens of uncertain familial placement in the order Verrucariales.

The type specimen was collected by French lichenologist Maurice Bouly de Lesdain from a wall in Les Baraques (Calais, France).

The genus has been subsequently been accepted by most lichenologists,[6] and is considered to be a member of the Verrucariales with uncertain familial placement.

[6] Botryolepraria species have a pale lime green byssoid (granular cottony) thallus made of free fungal hyphae.

Botryolepraria lesdainii produces lesdainin (6-α-acetoxyhopan-22-ol), a terpenoid compound; zeorin is an accompanying lichen product that also occurs in B. neotropica.