[4][5] It has been implicated in the widespread mortality of baobab (Adansonia digitata) trees in Southern Africa.

[6] L. theobromae causes diseases such as dieback, blights, and root rot in a variety of different hosts in tropical and subtropical regions.

In the trunk and cordon of the plant symptoms include cankers coming out of the wounds, wedge shaped lesions when cut in cross sections and dieback.

As tissue damage advances around the initial site of infection, the formation of cankers and cell death - or necrosis - will cause eventual dieback of the wood.

Under certain conditions, pseudothecia will grow on the surface of cankers and produce ascospores, which - like conidia - will disperse to infect surrounding wounds.