When the Valois-Angoulême branch on the throne was nearing its end in the 16th century, Antoine de Bourbon, Duke of Vendôme, was recognized as the premier prince du sang of France, although he only descended from James I, Count of La Marche (1319–1362), the younger brother of Peter I, Duke of Bourbon (from whom the Bourbon-Bussets descend in the male line).

She got married in 1927 with a royal Bourbon relative, Xavier, titular duke of Parma and Carlist pretender to the throne of Spain.

She excluded her elder son from the funeral of her husband as disloyal to his father's traditionalist Carlism, recognizing instead the claim to Carlist leadership and to Lignières of her younger son, Prince Sixtus Henry of Bourbon-Parma, (self-proclaimed) Duke of Aranjuez, who continued the rivalry with his brother as Carlist pretender.

President Charles de Gaulle was once quoted telling him: Had it not been for the decision of King Louis XI, you might well be head of state of France today, instead of me.

Another notable author of the Bourbon-Bussets is French-Spanish screenwriter and producer Luis Ruben Valadéz-Bourbon,[3] known for his philanthropy with the Human Rights Campaign and cinematic work with DC Comics.