The outcome of the First World War and change of Prussia to a Free State had little influence on the competition as, unlike other regions of Germany, Brandenburg did not lose any territory.

In 1933, associations throughout the country, including those in Berlin, were disbanded under the Nazi regime and reorganized into 16 regional leagues, or Gauligen, playing for a single national championship.

From 1903 to 1911, the Märkischer Fußball-Bund, named after the Mittelmark, existed in parallel with the Verband Berliner Ballspielvereine and both sent their champions to the German football championship.

To determine the champion, a two leg decider was played between Britannia Berlin and BFC Preussen with the former winning both games and earning its first league title.

Because of the top two teams finishing on equal points, a final had to be played once more, this time BFC Preussen coming out the winner.

[4] Expanded to nine clubs for 1900, the league champion won the Brandenburg title outright at this edition, BFC Preussen winning all of its 16 games.

[5] The following season, only seven clubs took part in the competition but for 1902 it was expanded to twelve teams in two divisions of six, with the two divisional winners playing out the Brandenburg champions.

Additionally, the league received some local competition with the March football championship being introduced, organised by the rival Märkischer Fußball-Bund.

Also, the German football championship was held for the first time, with the Brandenburg champion, Britannia Berlin, losing 1–3 against VfB Leipzig, who went on to win the title.

[7] Unchanged in format and modus, the league winner was once more Britannia Berlin with the club reaching the final of the German championship, too.

[7] In 1910, the two rival leagues continued their stand-off and the March champion, SC Tasmania 1900 Berlin, actually reached the semi-finals of the national championship while BFC Preussen was knocked out in the first round.

For 1923, both divisions operated on a strength of ten clubs, now renamed Oberliga Berlin-Brandenburg, and champions Union Oberschöneweide reached the national final, losing 0–3 to Hamburger SV.

Hertha BSC was to win the league seven consecutive times from 1925 to 1931, the last four of those by beating Tennis Borussia Berlin in the final, laying the foundations to a still existing rivalry.

[13] From 1925, an expanded finals round also meant that Brandenburg was allowed to send the championship finalist to the national title games as well.

[15] The 1932 season saw the end of Hertha's seven-year run; the club came second in its division and missed out on taking part in the Brandenburg finals.

[15] The last Brandenburg championship in 1933 was won by Hertha BSC once more, but the club's golden age had gone and it made a first-round exit to SV Hindenburg Allenstein at the national finals.