After a college basketball career with the Ohio Bobcats, leading the NCAA in rebounding in 2002–03, he was selected by the Boston Celtics in the second round of the 2003 NBA draft.

[1] Hunter ranked third for scoring (11.3 ppg) and second in rebounds (6.2 rpg) during his freshman year in 1999–2000, leading to a selection to the MAC All-Freshman Team.

[2] Playing more than nearly 33 minutes per game (first for the team) during his sophomore year, he finished in the conference top five for scoring (18.1 ppg) and rebounding (9.4 rpg, 23rd in nation).

Brandon was then signed by the Cleveland Cavaliers on October 3, 2006, joining LeBron James and playing in the NBA Summer League before being released two weeks later.

[7] Returning to the U.S. after the end of the season, he was signed by the Cleveland Cavaliers on October 3, 2006, playing in the NBA Summer League before being released two weeks later.

Hunter joined Capitanes de Arecibo of the Puerto Rican Baloncesto Superior Nacional later in 2008, leaving in May over disagreements due to him attending tryouts in the U.S.,[8] he then played in the Summer League for the New York Knicks.

Hunter returned to Italy for the fourth consecutive year, this time with Premiata Montegranaro, he finished the 2008–09 season as the league's best rebounder.

[10] Hunter joined Aliağa Petkim of the Turkish Basketball League, playing part of 2010–11 there before finishing the season with Latvians BK Ventspils.

[11] He stayed until April 2013, again signing as an injury replacement for French team ALM Évreux Basket, of the second division Pro B.

[12] A stint with Uruguayan champion Club Atlético Aguada of the Liga Uruguaya de Basketball from August to November 2013 was his last playing experience.