Brandon Charles Kolb (born November 20, 1973) is a former right-handed relief pitcher in Major League Baseball who played for the San Diego Padres and Milwaukee Brewers in 2000 and 2001.

Deciding not to sign, he would have to wait until 1995 to be drafted again, when he was selected by the Padres in the fourth round.

Although he struck out one batter in the single inning he pitched that game, he also gave up two hits and an earned run.

The players to be named would end up being Will Cunnane for the Padres and minor leaguer Chad Green of the Brewers.

He did not give up a single earned run until his fifth appearance of 2001, but he still posted a season ERA of 13.03.

He gave up six home runs in 92⁄3 innings of work, including three in one inning—on June 20 against the Cincinnati Reds, Kolb gave up home runs to Sean Casey, Michael Tucker, and Pokey Reese.