Prideaux spent most of his professional career in Major League Soccer, playing for the Kansas City Wizards, D.C. United, the Colorado Rapids and Chicago Fire.

Prideaux's performance in the A-League attracted the attention of MLS, and he signed with the Kansas City Wizards for the 1999 season; he played in 15 games, starting 8, registering one assist.

In 2005, he resumed his regular role, starting 28 of 29 games, but served primarily as a backup in 2006, playing in only 9 matches after suffering a knee injury.

While in D.C., Prideaux coached the NCSL division 1 Arlington Warriors, and led them to great success in Metro area league.

[5] Prideaux was waived by the Colorado Rapids on March 4, 2008, and was picked up by the Chicago Fire in the MLS Waiver Draft.