Stokley also played for the Indianapolis Colts, Seattle Seahawks, New York Giants, and Denver Broncos, earning two Super Bowl wins during his career.

His father, Nelson Stokley, played college football at LSU and was the head coach of the Louisiana–Lafayette Ragin' Cajuns from 1986 to 1998.

[2] Stokley attended Ovey Comeaux High School (Lafayette, Louisiana) and was a letterman in football, basketball, and baseball.

Furthermore, the TD catch made the 2004 Colts the first NFL team to have three WRs with 1,000 receiving yards and 10 touchdowns or more in a season, the other two being Reggie Wayne and Marvin Harrison.

In a memorable play from the Broncos' 2009 season opener, Stokley caught a pass intended for teammate Brandon Marshall that was tipped by Cincinnati Bengal Leon Hall, and took it 87 yards into the end zone for the winning score.

This ensured a win for the Broncos, who were trailing the Cincinnati Bengals 7–6 with 28 seconds left before Stokley's touchdown reception.

Stokley attributed the clock-burning run to having done so in video games "probably hundreds of times",[5] and it can be seen in the introduction of Madden NFL 11.

[6] Later that season, in week 16 against the Philadelphia Eagles, he was ejected from the game after slapping back judge Todd Prukop's hand in retaliation for a no pass interference call.

His performance was one of the keys to the 7-9 Seahawks' surprise upset of the defending Super Bowl champion New Orleans Saints.

On April 16, 2012, Stokley agreed to a one-year contract to return to the Denver Broncos, reuniting him with his former quarterback, Peyton Manning.

[11] Stokley suffered a concussion in a Week 14 victory over the Minnesota Vikings and was subsequently placed on injured reserve, ending his season.