[3][6] Rebecca Reggio is the current principal of Brandywine High School.

Its building was designed by Wilmington architects Whiteside, Moeckel & Carbonell in the International Style and completed in 1959.

[8] Brandywine is a member of the Delaware Interscholastic Athletic Association (DIAA).

[9] The Bulldogs compete in Flight B of the Blue Hen Conference with a full slate of teams in all three sports seasons:[10] Brandywine's sports include: cross country, field hockey, football, soccer, volleyball, cheerleading, basketball, swimming, wrestling, cheerleading, indoor track, baseball, softball, golf, lacrosse, tennis, and track and field.

[11] In 2021, U.S. News & World Report ranked Brandywine #5,392 out of almost 24,000 public schools across the United States[12] and Niche ranked it in the top 50% best public schools for athletes in New Castle County.