Brekov is a village and municipality in the Humenné District in the Prešov Region of north-east Slovakia.

The municipality lies at an altitude of 145 metres and covers an area of 9.725 km2.

Situated on a limestone bedrock hill at an altitude of roughly 480 m above sea level, Brekov castle was founded in the late second half of the 13th century.

It went through various owners during its history, though the longest ownership was by the Drugeth noble family, residing in nearby Humenné.

The castle was damaged in the 1640s and despite some repairs, it was abandoned and fell into ruin after 1684.