[1] Hanifee made his professional debut in 2017 with the Low–A Aberdeen IronBirds, starting 12 games and posting a 7–3 record and 2.75 ERA with 44 strikeouts.

[2] He spent the 2018 season with the Single–A Delmarva Shorebirds, starting 23 contests and logging an 8–6 record and 2.86 ERA with 85 strikeouts across 132.0 innings pitched.

[3] In 2019, Hanifee played for the High–A Frederick Keys, making 24 appearances and registering a 9–10 record and 4.60 ERA with 78 strikeouts across 129.0 innings of work.

[5] He returned from injury in 2022, playing for the Double–A Bowie Baysox, Aberdeen, and the rookie–level Florida Complex League Orioles.

He was assigned to the Triple–A Toledo Mud Hens,[7] for whom he made 25 appearances (13 starts) and logged a 2–8 record and 4.38 ERA with 82 strikeouts.