[3] Returning to Florida State in 2018, he tore the ulnar collateral ligament of the elbow and had Tommy John surgery.

[3] He made his professional debut in 2019, appearing in 13 games for the rookie-level AZL Diamondbacks and the Low-A Hillsboro Hops, where he logged a 2.39 ERA across 37.2 innings pitched.

[5] Holton split the 2021 season between the Double-A Amarillo Sod Poodles and the Triple-A Reno Aces, but struggled to a 6.72 ERA with 78 strikeouts in 64.1 innings pitched across 26 appearances.

[7] He made his MLB debut that night, tossing a scoreless inning of relief against the St. Louis Cardinals.

In 2024, Holton filled multiple roles for the Tigers, from opener to middle relief to occasional closer.