A redistricting bill was passed by both houses of the Indiana General Assembly in April 2011[2][3] and signed into law by Governor Mitch Daniels on May 10, 2011.

[2] Prior to announcing his Senate campaign, Donnelly commented that he was confident that a Democrat would be able to win the district, noting that then-Senator Barack Obama would have received 49% of the vote in the district in the 2008 presidential election had it been held under the newly drawn boundaries.

Rokita's home lies "about 500 yards" outside the boundaries of the newly drawn 4th district, a phenomenon he attributed in May 2011 to "a kind of comeuppance thing" on the part of members of the Indiana General Assembly in return for his having supported a nonpartisan redistricting process during his tenure as Secretary of State of Indiana.

[29] Organizations The 6th district was made more favorable to Republicans in redistricting,[36] and now stretches from Muncie to the Ohio River.

[2] Republican incumbent Mike Pence announced in May 2011 that he would run for Governor of Indiana rather than for re-election to the House of Representatives.

[50] Former state representative Dave Crooks was endorsed as the Democratic nominee by party leaders on December 10, 2011.