Brendan Murphy AC (born 1955) is an Australian public servant, health executive and nephrologist who served as the Chief Medical Officer (CMO) of Australia from 4 October 2016 before serving as the Secretary of the Department of Health from 13 July 2020 until his retirement on 6 July 2023.

[4] Murphy was appointed CMO of Australia on 4 October 2016, when he replaced Chris Baggoley.

[8] Murphy was also head of the Australian Health Protection Principal Committee[9] and in that role an adviser to the National Cabinet of Australia created to respond to the pandemic.

[12] His deputy, Paul Kelly, is acting the role of CMO until a new appointment is made.

[14] In June 2022, Murphy was appointed Companion of the Order of Australia in the 2022 Queen's Birthday Honours for "eminent service to medical administration and community health, particularly as Chief Medical Officer, and to nephrology, to research and innovation, and to professional organisations".