He is most notable for leading the team that co-created Google Maps and his tenures as the CTO of Facebook (now Meta Platforms), as the chairman of Twitter, Inc.'s board of directors prior to its acquisition by Elon Musk, and as the co-CEO of Salesforce (alongside co-founder Marc Benioff).

He attended Stanford University, where he earned his bachelor's and master's degree in computer science in 2002 and 2003, respectively.

[9] He remained in the position until the entire board of directors was dissolved following the acquisition of Twitter by Elon Musk in October 2022.

[16] He also led the creation of a system dubbed Customer 360 at Salesforce[17] and started an associate product manager program at the company.

[9] On November 30, 2022, it was announced that Taylor would be stepping down as co-CEO and vice chair at Salesforce at the end of January 2023.

[20][21] In November 2023, Taylor replaced Greg Brockman as the chairman of OpenAI when Sam Altman was briefly ousted and reinstated as CEO of the company by its board members.