Brian Edward Barkley (born December 8, 1975) is an American former professional baseball player.

The 6 ft 2 in (1.88 m), 180 lb (82 kg) left-hander was a relief pitcher in Major League Baseball who worked in six games pitched for the Boston Red Sox in the 1998 season.

[2] In his one-season career, Barkley posted an 0–0 record with two strikeouts, 16 hits allowed (including two home runs and nine bases on balls in 11 innings pitched).

[3] Barkley is the grandson of Red Barkley, who played for the St. Louis Browns, Boston Bees and Brooklyn Dodgers between 1937 and 1943.

[4] Barkley graduated from the Texas College of Osteopathic Medicine in 2013 and completed his residency at the Scott & White Pediatrics Residency Program located in Temple, Texas.