[4] Deese worked as a junior fellow at the Carnegie Endowment for International Peace and as a research assistant at the Center for Global Development,[5] hired by founder Nancy Birdsall, according to The New York Times, where he co-authored the book Delivering on Debt Relief.

According to Biden, "Brian has a unique ability to translate complex policy challenges into concrete actions that improve the lives of American people."

Between the spring and fall of 2021, Brian Deese, Steve Ricchetti, and Louisa Terrell were frequent visitors to Capitol Hill, brokering policy conversations and building a coalition of support among Senate Democrats and Republicans.

[31] In April 2022, Deese laid out the case behind the administration's pursuit of a modern industrial strategy, stating: “The question should move from ‘why should we pursue an industrial strategy?’ to ‘how do we pursue one successfully?’”[32] In October 2022, Deese described a modern American industrial strategy as "the best antidote to [the] risk of lower productivity and lower economic capacity in the years ahead," citing the need for strategic, long-term investments in high-return sectors, where public capital helps reduce price pressures, taps into growing global demand, and increases the country's export competitiveness.

[33] Deese worked closely with Secretary Gina Raimondo to design and advocate for the CHIPS and Science Act, viewing it as an essential component to the President's industrial strategy.

Deese also served as President Biden's primary policy negotiator for key climate, health, and tax reform measures passed in the Inflation Reduction Act.

[34] Deese was particularly involved in landing the clean energy and climate provisions, visiting West Virginia with Senator Manchin in March 2022.

"Coal and energy communities helped make America what it is, the strongest economy in the world and the global leader of democracy," Deese wrote.

"[36] Beyond IRA passage, Deese developed a reputation for weaving climate action into the fabric of White House economic policymaking.

He pushed to establish the first-ever White House Competition Council, which he chairs, and has spoken publicly on the need to increase entrepreneurship and reduce barriers to entry in key U.S.

Deese's role as Fellow includes research and development of strategies to address climate change and promote sustainable economic growth.

MIT anticipates his arrival will foster a productive nexus between policy-making and technological innovation, vital for addressing the global climate crisis.