[1] As an independent scientist at the University of Toronto, he developed a rational approach to chiral diphosphine ligands, the premier member being chiraphos.

[10][11][12] Other areas of research included hydroacylation catalysis and the development of ligands that mimic the spectroscopic properties of the blue copper proteins.

[13] After his retirement, Bosnich questioned the Royal Society's position on climate change, which is the scientific consensus on the subject.

His design, synthesis and studies of the ligands, chiraphos and prophos, represent a major accomplishment and have contributed enormously to our understanding of the mechanisms of chiral recognition and asymmetric catalysis.

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