[3] Following the 2017 legislative election, Bourguignon stood as a candidate for the National Assembly's presidency;[4] in an internal vote within the LREM parliamentary group, she lost against François de Rugy.

[6] In what was the first victory of LREM in a legislative by-election, Bourguignon managed to win with 62.05% of the vote (60.8% in the previous election) over the National Rally (RN) candidate Marie-Christine Bourgeois in 2021.

[8] During her time at the Ministry of Solidarity and Health, Bourguignon led the government’s efforts in 2022 to file a criminal complaint against home care group Orpea [fr] over allegations of mistreatment of elderly patients in the period from 2017 to 2020.

[9] In May 2018, Bourguignon co-sponsored an initiative in favour of a bioethics law extending to homosexual and single women free access to artificial reproduction such as in vitro fertilisation (IVF) under France's national health insurance; it was one of the campaign promises of President Emmanuel Macron and marked the first major social reform of his five-year term.

[10] In July 2019, Bourguignon voted in favor of the French ratification of the European Union’s Comprehensive Economic and Trade Agreement (CETA) with Canada.