In 1795–1796, she made one complete voyage as a slave ship in the triangular trade, taking enslaved people from West Africa to Jamaica.

A French privteer captured her in 1797 in a notable single ship action as Britannia was on the outward leg of her second voyage.

[2] 1st slave trading voyage (1795–1796): Captain Matthews sailed from Liverpool on 10 April 1795 and arrived in Africa on 27 July.

[6] As Pince was sailing from Liverpool to Africa, a French privateer captured him and took Britannia to Nantes.

In the ensuing engagement Britannia had one man killed and several wounded, and suffered much damage before she struck after an hour's combat.