[2] After graduating from Heyworth High School in 2004,[3] she earned a Bachelor of Science in Communication from Northwestern University in 2008.

[5] Lower had a recurring role as technology expert Tanya Sitkowsky in the 2011 series Unforgettable.

[6] In 2015, she began her breakout role in the FXX comedy series Man Seeking Woman, portraying Liz Greenberg, the sister of the main protagonist.

[7] Lower was signed for a recurring role in the Hulu original series Casual in season 2, as Sarah Finn.

During the hiatus between seasons of Severance, she joined St. Louis' Circus Flora, playing a character in their "Quest for the Innkeeper's Cask" performance for a month.