Snow is the co-founder of the Love Is Louder movement, a project by the not-for-profit Jed Foundation, dedicated to stop bullying in schools.

[9] She played Meg Pryor on NBC's drama series American Dreams[10] and neo-Nazi high school student Ariel Alderman on the third season of FX's Nip/Tuck.

[12] Snow appeared in the teen romantic comedy film John Tucker Must Die (2006) opposite Jesse Metcalfe.

She also portrayed a young woman afflicted with bipolar disorder in the season seven finale of Law & Order: Special Victims Unit.

[14] Snow appeared in Hairspray (2007), a film adaptation of the Broadway musical, playing Amber Von Tussle, the daughter of Michelle Pfeiffer's character.

She played the lead role of Donna Keppel in the slasher film Prom Night (2008), which was released on April 11, 2008, and grossed $57.2 million at the box office.

She again reprised her role a final time in Pitch Perfect 3 (2017), which received mixed reviews from critics and grossed $185 million worldwide.

[29] This role marked the first time Snow portrayed a mother, saying: "I think what I related to is that I'm not a mom yet, or necessarily, but I do think a lot of women have to face really hard challenges and yet be very strong and stoic and silent in a way.

"[29] Snow has supported numerous charities, including Clothes Off Our Back, Declare Yourself, Do Something, Feeding America, Habitat For Humanity, Point Foundation, Red Cross, Soles4Souls, The Heart Truth, The Trevor Project, Stomp Out Bullying and The Art of Elysium.

"Whether it's a child struggling to go to school in Kenya, or an American who needs a pair of work boots, Soles4Souls is there to answer the simple requests of millions of people.

Thousands of individuals, campuses, and communities have used Love is Louder's programs, events and clubs to address issues such as bullying, body image, discrimination, and depression.

[33] Together with good friend Jesper Guest, Snow founded the charity September Letters 2016 for mental challenges awareness, encouraging people to share stories in a meaningful communication.