[1] She is currently the lead vocalist and guitarist with Brix & the Extricated, along with brothers Steve and Paul Hanley, both of whom were long time musicians in the Fall.

[5] Studying theatre and literature at Bennington College in Vermont,[6] Smith formed a group, Banda Dratsing, in which she performed as bassist/vocalist; she adopted the name "Brix" after the Clash's 1979 song "The Guns of Brixton".

She co-wrote some of the best-regarded Fall tracks from the period, and is acknowledged for introducing a more mainstream, pop-oriented element to the group's sound.

The group released four singles for the Fall's label Beggars Banquet Records in 1985 and 1986, including a cover of Strawberry Alarm Clock's "Incense and Peppermints".

[3] Hole guitarist Eric Erlandson, while supportive of Melissa Auf der Maur as Pfaff's replacement, later commented that he was a huge fan of Brix and expressed regret that he didn't get a chance to play with her in the group.

In 2022, Smith announced a new album, Valley of the Dolls, co-written with Youth from Killing Joke, and a new live band to perform this material, containing Debbie Googe and Jen Macro of My Bloody Valentine, as well as Vas Antoniadou and Ros Cairney from deux furieuses.

The album contains guest contributions from Susanna Hoffs of The Bangles and Siobhan Fahey and is planned for release in 2023 on Republic of Music.

She also appeared on Animal Planet UK's Top Dog, The Culture Show on BBC Two, John Peel's Record Box, LK Today's 'What's Hot and What's Not' segment[13] and Sky 1's Angela and Friends.