There is at least one reported case of bromoderma caused by excessive consumption of a soft drink (Ruby Red Squirt) containing brominated vegetable oil.
[2] The disease's symptoms can range from a mild acneiform rash with papules and pustules to more severe conditions like panniculitis, ulcers, and vegetative nodules, also referred to as tuberous or vegetating bromoderma.
[3][4] One could characterize bromoderma as a kind of delayed hypersensitivity reaction, even though its pathogenesis is still unknown.
[5] Lesions can develop as soon as eight days after the medicine is first administered, but they typically do so after a prolonged period of use.
High sebaceous gland concentrations on the skin are typically the site of lesions.