He played in Major League Baseball (MLB) from 2008 to 2014 for the Oakland Athletics, Atlanta Braves, Milwaukee Brewers, and Tampa Bay Rays, and San Diego Padres.

[5] Conrad became a free agent at the end of the season and signed a minor league contract with an invitation to spring training with the Atlanta Braves in November 2008.

[7] On July 7, 2009, Conrad hit his first career Major League triple off Chicago Cubs pitcher Carlos Zambrano.

He hit a walk-off grand slam against Cincinnati Reds pitcher, Francisco Cordero, to cap an eight-run comeback for his team.

[10] On June 12, 2010, he dropped down an eventual game winning suicide squeeze bunt to score Gregor Blanco in the 9th inning against the Minnesota Twins.

[11] On July 24, 2010, Conrad hit his second go-ahead grand slam of the year, in the 8th inning against Burke Badenhop of the Florida Marlins.

[14] In game three of the 2010 NLDS, Conrad made three errors in a loss to the San Francisco Giants, who would eventually go on to win the World Series.

On May 1, 2011, in a game against the St. Louis Cardinals, Conrad came off the bench to hit a game-winning single in the bottom of the 9th inning to give the Braves a 6–5 victory.

[18] Later in the month on May 25 in a game against the Pittsburgh Pirates, Conrad launched a go-ahead and ultimately game-winning 2-run homer in the 11th inning.

[22] On June 24, Conrad hit a pair of two-run doubles off Philadelphia Phillies pitcher Cliff Lee to secure a sweep in a day-night doubleheader.

[25] On January 4, 2014, Conrad and the San Diego Padres agreed to a minor league contract that did not include a spring training invitation.

[citation needed] In December 2016, Conrad signed a minor league contract with the Kansas City Royals.